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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SGK2
All Species:
28.48
Human Site:
T250
Identified Species:
52.22
UniProt:
Q9HBY8
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9HBY8
NP_057360.2
427
47604
T250
E
G
V
E
P
E
D
T
T
S
T
F
C
G
T
Chimpanzee
Pan troglodytes
XP_001142856
441
49512
T264
E
G
V
E
P
E
D
T
T
S
T
F
C
G
T
Rhesus Macaque
Macaca mulatta
XP_001083986
450
50817
T273
E
G
V
E
P
E
E
T
T
S
T
F
C
G
T
Dog
Lupus familis
XP_849801
431
48950
T253
E
N
I
E
H
N
G
T
T
S
T
F
C
G
T
Cat
Felis silvestris
Mouse
Mus musculus
Q9QZS5
367
41341
T193
E
P
E
E
T
T
S
T
F
C
G
T
P
E
Y
Rat
Rattus norvegicus
Q8R4U9
367
41343
T193
E
P
E
E
T
T
S
T
F
C
G
T
P
E
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511204
429
48309
T251
E
G
M
E
P
E
E
T
T
S
T
F
C
G
T
Chicken
Gallus gallus
Q6U1I9
432
48872
T254
E
N
I
E
H
N
G
T
T
S
T
F
C
G
T
Frog
Xenopus laevis
Q6GLY8
434
49082
I256
E
N
I
E
P
N
G
I
T
S
T
F
C
G
T
Zebra Danio
Brachydanio rerio
Q7ZTW4
433
48964
T255
E
N
I
E
P
N
G
T
T
S
T
F
C
G
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q8INB9
611
68466
T420
E
D
I
T
Y
G
R
T
T
K
T
F
C
G
T
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q2PJ68
463
54273
Q286
G
L
C
K
E
D
M
Q
G
S
K
T
T
S
T
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P12688
680
76461
K501
L
N
M
K
D
D
D
K
T
D
T
F
C
G
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
85.9
83.5
62.4
N.A.
81
80.5
N.A.
73.6
62
60.3
63.5
N.A.
33.8
N.A.
41.9
N.A.
Protein Similarity:
100
87.7
86.2
75.8
N.A.
83.6
83.3
N.A.
80.8
75.4
74.8
74.3
N.A.
45.3
N.A.
58.5
N.A.
P-Site Identity:
100
100
93.3
66.6
N.A.
20
20
N.A.
86.6
66.6
66.6
73.3
N.A.
53.3
N.A.
13.3
N.A.
P-Site Similarity:
100
100
100
73.3
N.A.
20
20
N.A.
100
73.3
73.3
80
N.A.
60
N.A.
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
30.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
40.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
46.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
66.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
8
0
0
0
0
0
0
16
0
0
77
0
0
% C
% Asp:
0
8
0
0
8
16
24
0
0
8
0
0
0
0
0
% D
% Glu:
85
0
16
77
8
31
16
0
0
0
0
0
0
16
0
% E
% Phe:
0
0
0
0
0
0
0
0
16
0
0
77
0
0
0
% F
% Gly:
8
31
0
0
0
8
31
0
8
0
16
0
0
77
0
% G
% His:
0
0
0
0
16
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
39
0
0
0
0
8
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
16
0
0
0
8
0
8
8
0
0
0
0
% K
% Leu:
8
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
16
0
0
0
8
0
0
0
0
0
0
0
0
% M
% Asn:
0
39
0
0
0
31
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
16
0
0
47
0
0
0
0
0
0
0
16
0
0
% P
% Gln:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
16
0
0
70
0
0
0
8
0
% S
% Thr:
0
0
0
8
16
16
0
77
77
0
77
24
8
0
85
% T
% Val:
0
0
24
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
16
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _